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A special place in the history of the "great royal wives' takes Hatshepsut. It was a "great tsarist wife" of her half brothers of Thutmose II. During this time, Hatshepsut was the "wife of the god Amun" (the highest rank of priestess in the temple of Amun at Karnak). After her husband's death she became regent, because of the small age her stepson Thutmose III of, the only male heir (born consort Isis), and rules successfully for 22 years. Although she and the other women ruled Egypt, Hatshepsut was the first woman to receive the title of pharaoh. After becoming Pharaoh, she appointed her daughter Neferuru high priestess, handing her the title "wife of the god Amun." Maybe her daughter was "great wife" of Tuthmosis III, but there is no evidence of their supposed marriage .